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Effects of sevoflurane with and without nitrous oxide onhuman cerebral circulation. Blebbing is caused by the detachment of theplasma membrane from underlying actin filaments ofthe cellcytoskeleton. ( a) A case of gastric diverticulum ( arrow-head) in a 56-year-old male. (2006) Grand rounds: headaches in angle-closureglaucoma. A 1997 study by Litvan et al.,showed extremely low sensitivity of the clinical diagnosisof CBD by neurologists (48.3%, at best), with false negativesbeing primarily diagnoses of PSP (Litvan et al., 1997). What are the causes of mid diastolic murmur (MDM)?A.